Effects of Colesevelam on Bowel Symptoms, Biomarkers, and Colonic Mucosal Gene Expression in Patients with Bile Acid Diarrhea in a Randomized Trial

BACKGROUND & AIMS: Approximately one-third of patients with IBS-diarrhea (IBS-D) have increased bile acid (BA) synthesis or excretion. An open-label study showed benefits of colesevelam on bowel functions, consistent with luminal BA sequestration by colesevelam. We compared the effects of colese...

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Detaylı Bibliyografya
Yayımlandı:Clin Gastroenterol Hepatol
Asıl Yazarlar: Vijayvargiya, Priya, Camilleri, Michael, Carlson, Paula, Nair, Asha, Nord, Sara Linker, Ryks, Michael, Rhoten, Deborah, Burton, Duane, Busciglio, Irene, Lueke, Alan, Harmsen, W. Scott, Donato, Leslie J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442687/
https://ncbi.nlm.nih.gov/pubmed/32088296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2020.02.027
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