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Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol
Cholesterol 25-hydroxylase (CH25H) is an interferon-stimulated gene that converts cholesterol to the oxysterol 25-hydroxycholesterol (25HC). Circulating 25HC modulates essential immunological processes including antiviral immunity, inflammasome activation and antibody class switching; and dysregulat...
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| Publicat a: | Nat Microbiol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442315/ https://ncbi.nlm.nih.gov/pubmed/32284563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-020-0701-5 |
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