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Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum

Recent studies using two cholesterol-binding bacterial toxin proteins, perfringolysin O (PFO) and domain 4 of anthrolysin O (ALOD4), have shown that cholesterol in the plasma membranes (PMs) of animal cells resides in three distinct pools. The first pool comprises mobile cholesterol, accessible to b...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Johnson, Kristen A., Endapally, Shreya, Vazquez, Danya C., Infante, Rodney E., Radhakrishnan, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873175/
https://ncbi.nlm.nih.gov/pubmed/31597703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010393
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