Reduced treatment frequencies with bumped kinase inhibitor 1369 are effective against porcine cystoisosporosis

Bumped kinase inhibitors (BKIs) are a new class of antiprotozoal drugs that target calcium-dependent protein kinase 1 (CDPK1) in various apicomplexan parasites. A multiple dose regimen of BKI 1369 has been shown to be highly effective against Cystoisospora suis (syn. Isospora suis), the causative ag...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Shrestha, Aruna, Ruttkowski, Bärbel, Greber, Patricia, Whitman, Grant R., Hulverson, Matthew A., Choi, Ryan, Michaels, Samantha A., Ojo, Kayode K., Van Voorhis, Wesley C., Joachim, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442133/
https://ncbi.nlm.nih.gov/pubmed/32861205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2020.08.005
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