Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer

Cervical cancer (CC) remains highest in the mortality of female reproductive system cancers, while cisplatin (CDDP) resistance is the one of main reasons for the lethality. Preceding evidence has supported that karyopherins are associated with chemoresistance. In this study, we simultaneously compar...

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Dades bibliogràfiques
Publicat a:Oncogene
Autors principals: Zhou, Yang, Liu, Fei, Xu, Qinyang, Yang, Bikang, Li, Xiao, Jiang, Shuheng, Hu, Lipeng, Zhang, Xueli, Zhu, Lili, Li, Qing, Zhu, Xiaolu, Shao, Hongfang, Dai, Miao, Shen, Yifei, Ni, Bo, Wang, Shuai, Zhang, Zhigang, Teng, Yincheng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441007/
https://ncbi.nlm.nih.gov/pubmed/32661323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1384-3
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