Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer

Cervical cancer (CC) remains highest in the mortality of female reproductive system cancers, while cisplatin (CDDP) resistance is the one of main reasons for the lethality. Preceding evidence has supported that karyopherins are associated with chemoresistance. In this study, we simultaneously compar...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Zhou, Yang, Liu, Fei, Xu, Qinyang, Yang, Bikang, Li, Xiao, Jiang, Shuheng, Hu, Lipeng, Zhang, Xueli, Zhu, Lili, Li, Qing, Zhu, Xiaolu, Shao, Hongfang, Dai, Miao, Shen, Yifei, Ni, Bo, Wang, Shuai, Zhang, Zhigang, Teng, Yincheng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441007/
https://ncbi.nlm.nih.gov/pubmed/32661323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1384-3
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