MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity

Localized prostate cancer develops very slowly in most men, with the androgen receptor (AR) and MYC transcription factors amongst the most well-characterized drivers of prostate tumorigenesis. Canonically, MYC up-regulation in luminal prostate cancer cells functions to oppose the terminally differen...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Whitlock, Nichelle C., Trostel, Shana Y., Wilkinson, Scott, Terrigino, Nicholas T., Hennigan, S. Thomas, Lake, Ross, Carrabba, Nicole V., Atway, Rayann, Walton, Elizabeth D., Gryder, Berkley E., Capaldo, Brian J., Ye, Huihui, Sowalsky, Adam G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441006/
https://ncbi.nlm.nih.gov/pubmed/32681068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01389-7
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