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MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity
Localized prostate cancer develops very slowly in most men, with the androgen receptor (AR) and MYC transcription factors amongst the most well-characterized drivers of prostate tumorigenesis. Canonically, MYC up-regulation in luminal prostate cancer cells functions to oppose the terminally differen...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7441006/ https://ncbi.nlm.nih.gov/pubmed/32681068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01389-7 |
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