Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus

Sensory inputs activate sparse neuronal ensembles in the dentate gyrus of the hippocampus, but how eligibility of individual neurons to recruitment is determined remains elusive. We identify thousands of largely bistable (CpG methylated or unmethylated) regions within neuronal gene bodies, establish...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Odell, Shannon C., Taki, Faten, Klein, Shifra Liba, Chen, Rosa J., Levine, Olivia B., Skelly, Mary Jane, Nabila, Anika, Brindley, Elizabeth, Toth, Judit Gal, Dündar, Friederike, Sheridan, Caroline K., Fetcho, Robert N., Alonso, Alicia, Liston, Conor, Landau, Dan A., Pleil, Kristen E., Toth, Miklos
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440841/
https://ncbi.nlm.nih.gov/pubmed/32579919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107789
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