Oral versus intramuscular administration of vitamin B12 for vitamin B12 deficiency in primary care: a pragmatic, randomised, non-inferiority clinical trial (OB12)

OBJECTIVES: To compare the effectiveness of oral versus intramuscular (IM) vitamin B(12) (VB12) in patients aged ≥65 years with VB12 deficiency. DESIGN: Pragmatic, randomised, non-inferiority, multicentre trial in 22 primary healthcare centres in Madrid (Spain). PARTICIPANTS: 283 patients ≥65 years...

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Veröffentlicht in:BMJ Open
Hauptverfasser: Sanz-Cuesta, Teresa, Escortell-Mayor, Esperanza, Cura-Gonzalez, Isabel, Martin-Fernandez, Jesus, Riesgo-Fuertes, Rosario, Garrido-Elustondo, Sofía, Mariño-Suárez, Jose Enrique, Álvarez-Villalba, Mar, Gómez-Gascón, Tomás, González-García, Inmaculada, González-Escobar, Paloma, Vargas-Machuca Cabañero, Concepción, Noguerol-Álvarez, Mar, García de Blas-González, Francisca, Baños-Morras, Raquel, Díaz-Laso, Concepción, Caballero-Ramírez, Nuria, Herrero de-Dios, Alicia, Fernández-García, Rosa, Herrero-Hernández, Jesús, Pose-García, Belen, Sevillano-Palmero, María Luisa, Mateo-Ruiz, Carmen, Medina-Bustillo, Beatriz, Aguilar-Jiménez, Monica
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
General practice / Family practice
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440823/
https://ncbi.nlm.nih.gov/pubmed/32819927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-033687
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