Oral versus intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency: a pragmatic, randomised, multicentre, non-inferiority clinical trial undertaken in the primary healthcare setting (Project OB12)

BACKGROUND: The oral administration of vitamin B12 offers a potentially simpler and cheaper alternative to parenteral administration, but its effectiveness has not been definitively demonstrated. The following protocol was designed to compare the effectiveness of orally and intramuscularly administe...

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Hauptverfasser: Sanz-Cuesta, Teresa, González-Escobar, Paloma, Riesgo-Fuertes, Rosario, Garrido-Elustondo, Sofía, del Cura-González, Isabel, Martín-Fernández, Jesús, Escortell-Mayor, Esperanza, Rodríguez-Salvanés, Francisco, García-Solano, Marta, González-González, Rocío, Martín-de la Sierra-San Agustín, María �ngeles, Olmedo-Lucerón, Carmen, Palmero, María Luisa Sevillano, Mateo-Ruiz, Carmen, Medina-Bustillo, Beatriz, Valdivia-Pérez, Antonio, Blas-González, Francisca García-de, Mariño-Suárez, José Enrique, Rodríguez-Barrientos, Ricardo, Ariza-Cardiel, Gloria, Cabello-Ballesteros, Luisa María, Polentinos-Castro, Elena, Rico-Blázquez, Milagros, Rodríguez-Monje, Ma Teresa, Soto-Díaz, Sonia, Martín-Iglesias, Susana, Rodríguez-González, Ramón, Bretón-Lesmes, Irene, Vicente-Herrero, María, Sánchez-Díaz, Jesús, Gómez-Gascón, Tomás, Drake-Canela, Mercedes, Barco, �ngel Asúnsolo-del
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Study Protocol
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403849/
https://ncbi.nlm.nih.gov/pubmed/22650964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2458-12-394
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