Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-α release in Burkholderia thailandensis infection in vitro

Melioidosis is an often-severe tropical infection caused by Burkholderia pseudomallei (Bp) with high associated morbidity and mortality. Burkholderia thailandensis (Bt) is a closely related surrogate that does not require BSL-3 conditions for study. Lactoferrin is an iron-binding glycoprotein that c...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Wright, Shelton W., Lovelace-Macon, Lara, Ducken, Deirdre, Tandhavanant, Sarunporn, Teparrukkul, Prapit, Hantrakun, Viriya, Limmathurotsakul, Direk, Chantratita, Narisara, West, T. Eoin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439809/
https://ncbi.nlm.nih.gov/pubmed/32764765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008495
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