Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis

Melioidosis, an infectious disease caused by the bacterium Burkholderia pseudomallei, is a common cause of sepsis in Southeast Asia. We investigated whether novel TLR1 coding variants are associated with outcome in Thai patients with melioidosis. We performed exonic sequencing on a discovery set of...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Wright, Shelton W., Emond, Mary J., Lovelace-Macon, Lara, Ducken, Deirdre, Kashima, James, Hantrakun, Viriya, Chierakul, Wirongrong, Teparrukkul, Prapit, Chantratita, Narisara, Limmathurotsakul, Direk, West, T. Eoin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455179/
https://ncbi.nlm.nih.gov/pubmed/30866782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1575172
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