Three Related Enzymes in Candida albicans Achieve Arginine- and Agmatine-Dependent Metabolism That Is Essential for Growth and Fungal Virulence

Amino acid metabolism is crucial for fungal growth and development. Ureohydrolases produce amines when acting on l-arginine, agmatine, and guanidinobutyrate (GB), and these enzymes generate ornithine (by arginase), putrescine (by agmatinase), or GABA (by 4-guanidinobutyrase or GBase). Candida albica...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Schaefer, Katja, Wagener, Jeanette, Ames, Ryan M., Christou, Stella, MacCallum, Donna M., Bates, Steven, Gow, Neil A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439472/
https://ncbi.nlm.nih.gov/pubmed/32788384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01845-20
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