The Mnn2 Mannosyltransferase Family Modulates Mannoprotein Fibril Length, Immune Recognition and Virulence of Candida albicans

The fungal cell wall is the first point of interaction between an invading fungal pathogen and the host immune system. The outer layer of the cell wall is comprised of GPI anchored proteins, which are post-translationally modified by both N- and O-linked glycans. These glycans are important pathogen...

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Main Authors: Hall, Rebecca A., Bates, Steven, Lenardon, Megan D., MacCallum, Donna M., Wagener, Jeanette, Lowman, Douglas W., Kruppa, Michael D., Williams, David L., Odds, Frank C., Brown, Alistair J. P., Gow, Neil A. R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636026/
https://ncbi.nlm.nih.gov/pubmed/23633946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003276
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