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Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

Nuclear pore complex components (Nups) have been implicated in transcriptional regulation, yet what regulatory steps are controlled by metazoan Nups remains unclear. We identified the presence of multiple Nups at promoters, enhancers, and insulators in the Drosophila genome. In line with this bindin...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Pascual-Garcia, Pau, Debo, Brian, Aleman, Jennifer R., Talamas, Jessica A., Lan, Yemin, Nguyen, Nha H., Won, Kyoung J., Capelson, Maya
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439321/
https://ncbi.nlm.nih.gov/pubmed/28366641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.02.020
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