Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis

The proliferation of vascular smooth muscle cells (VSMCs) induced by oxidative injury is one of the main features in diabetes-accelerated atherosclerosis. Geranylgeranyl transferase-I (GGTase-I) is an essential enzyme mediating posttranslational modification, especially the geranylgeranylation of sm...

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Detalles Bibliográficos
Publicado en:J Diabetes Res
Main Authors: Chen, Guo-Ping, Yang, Jian, Qian, Guo-Feng, Xu, Wei-Wei, Zhang, Xiao-Qin
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439171/
https://ncbi.nlm.nih.gov/pubmed/32851097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7574245
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