Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis

The proliferation of vascular smooth muscle cells (VSMCs) induced by oxidative injury is one of the main features in diabetes-accelerated atherosclerosis. Geranylgeranyl transferase-I (GGTase-I) is an essential enzyme mediating posttranslational modification, especially the geranylgeranylation of sm...

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Vydáno v:J Diabetes Res
Hlavní autoři: Chen, Guo-Ping, Yang, Jian, Qian, Guo-Feng, Xu, Wei-Wei, Zhang, Xiao-Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439171/
https://ncbi.nlm.nih.gov/pubmed/32851097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7574245
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