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Antiproliferative activities of tricyclic amides derived from β-caryophyllene via the Ritter reaction against MDA-MB-231 breast cancer cells

A library of novel tricyclic amides has been synthesised via the Ritter reaction from β-caryophyllene 1 and its monoepoxy derivative 4. The compounds were assessed for antiproliferative activities against the aggressive MDA-MB-231 breast cancer cell line. Of the synthesised compounds, eight were act...

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Pubblicato in:RSC Med Chem
Autori principali: Xu, XiXi, Roseblade, Ariane, Rawling, Tristan, Ung, Alison T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439098/
https://ncbi.nlm.nih.gov/pubmed/33479611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00237e
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