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Antiproliferative activities of alkaloid-like compounds

Tricyclic alkaloid-like compounds were synthesised in a few steps, via the bridging Ritter reaction. The compounds were evaluated for their antiproliferative activity against the MCF-7 and the aggressive MDA-MB-231 breast cancer cells. The anti-cancer activities of 2c were found to be selective towa...

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Publicat a:Medchemcomm
Autors principals: Xu, XiXi, Rawling, Tristan, Roseblade, Ariane, Bishop, Roger, Ung, Alison T.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072216/
https://ncbi.nlm.nih.gov/pubmed/30108728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00435d
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