The Role of GSK3 and its Reversal with GSK3 Antagonism in Everolimus Resistance

Pancreatic neuroendocrine tumors (panNETs) are often inoperable at diagnosis. The mTORC1 inhibitor everolimus has been approved for the treatment of advanced NETs. However, the regular development of resistance to everolimus limits its clinical efficacy. We established two independent everolimus-res...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Prada, Elke Tatjana Aristizabal, Spöttl, Gerald, Maurer, Julian, Lauseker, Michael, Koziolek, Eva Jolanthe, Schrader, Jörg, Grossman, Ashley, Pacak, Karel, Beuschlein, Felix, Auernhammer, Christoph Joseph, Nölting, Svenja
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439002/
https://ncbi.nlm.nih.gov/pubmed/29895527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-18-0159
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados