The MTH1 inhibitor TH588 demonstrates anti-tumoral effects alone and in combination with everolimus, 5-FU and gamma-irradiation in neuroendocrine tumor cells

Modulation of the redox system in cancer cells has been considered a promising target for anti-cancer therapy. The novel MTH1 inhibitor TH588 proved tremendous potential in terms of cancer cell eradication, yet its specificity has been questioned by recent reports, indicating that TH588 may also ind...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Aristizabal Prada, Elke Tatjana, Orth, Michael, Nölting, Svenja, Spöttl, Gerald, Maurer, Julian, Auernhammer, Christoph
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444855/
https://ncbi.nlm.nih.gov/pubmed/28542590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178375
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk