Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4

Background: Oral commensals contribute to microbe-host symbiosis in periodontal homeostasis, and Porphyromonas gingivalis (P. gingivalis) as the keystone pathogen critically accounts for the shift of symbiosis to dysbiosis and periodontal destruction. Nucleotide-binding oligomerization domain (NOD)-...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Ding, Pei-Hui, Yang, Meng-Xin, Wang, Na-Na, Jin, Li-Jian, Dong, Yan, Cai, Xia, Chen, Li-Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438778/
https://ncbi.nlm.nih.gov/pubmed/32903638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01881
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