CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas

Cyclin-Dependent Kinases (CDKs) are well-known reliable targets for cancer treatment being often deregulated. Among them, since the transcription-associated CDK9 represents the sentry of cell transcriptional homeostasis, it can be a valuable target for managing cancers in which the transcriptional m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Cassandri, Matteo, Fioravanti, Rossella, Pomella, Silvia, Valente, Sergio, Rotili, Dante, Del Baldo, Giada, De Angelis, Biagio, Rota, Rossella, Mai, Antonello
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438590/
https://ncbi.nlm.nih.gov/pubmed/32903585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01230
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