Chemotherapeutic resistance of head and neck squamous cell carcinoma is mediated by EpCAM induction driven by IL-6/p62 associated Nrf2-antioxidant pathway activation

Overexpression of epithelial cell adhesion molecule (EpCAM) has been associated with chemotherapeutic resistance, leads to aggressive tumor behavior, and results in an adverse clinical outcome. The molecular mechanism by which EpCAM enrichment is linked to therapeutic resistance via Nrf2, a key regu...

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Publicado no:Cell Death Dis
Main Authors: Noman, Abu Shadat M., Parag, Rashed R., Rashid, Muhammad I., Islam, Shafiqul, Rahman, Mohammad Z., Chowdhury, Ali A., Sultana, Afrin, Jerin, Chandsultana, Siddiqua, Ayesha, Rahman, Lutfur, Nayeem, Junayed, Akther, Sonam, Baidya, Sunanda, Shil, Rajib K., Rahman, Mizanur, Shirin, Afsana, Mahmud, Reaz, Hossain, S. M. Ikram, Sumi, Sharmin A., Chowdhury, Arfina, Basher, Shabnam B., Hasan, Abul, Bithy, Shammy, Aklima, Jannatul, Chowdhury, Nabila, Hasan, Muhammad N., Banu, Tahmina, Chowdhury, Srikanta, Hossain, Muhammad M., Yeger, Herman, Farhat, Walid A., Islam, Syed S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438524/
https://ncbi.nlm.nih.gov/pubmed/32814771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02907-x
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