Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer

BACKGROUND: Sonic hedgehog (Shh) and Nrf2 play a critical role in chemotherapeutic resistance. These two genes have been found to be dysregulated in head and neck squamous cell carcinomas (HNSCC). The purpose of this study was to analyze the expression, function and clinical prognostic relationship...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Noman, Abu Shadat M., Parag, Rashed R., Rashid, Muhammad I., Rahman, Mohammad Z., Chowdhury, Ali A., Sultana, Afrin, Jerin, Chandsultana, Siddiqua, Ayesha, Rahman, Lutfur, Shirin, Afsana, Nayeem, Junayed, Mahmud, Reaz, Akther, Sonam, Shil, Rajib K., Hossain, Ikram, Alam, Sharmin, Chowdhury, Arfina, Basher, Shabnam B., Hasan, Abul, Bithy, Shammy, Aklima, Jannatul, Rahman, Mizanur, Chowdhury, Nabila, Banu, Tahmina, Karakas, Bedri, Yeger, Herman, Farhat, Walid A., Islam, Syed S.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074584/
https://ncbi.nlm.nih.gov/pubmed/32206093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920911229
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