WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m(6)A-dependent manner

N(6)-methyladenosine (m(6)A) regulators are involved in the progression of various cancers via regulating m(6)A modification. However, the potential role and mechanism of the m(6)A modification in osteosarcoma remains obscure. In this study, WTAP was found to be highly expressed in osteosarcoma tiss...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chen, Shijie, Li, Yuezhan, Zhi, Shuang, Ding, Zhiyu, Wang, Weiguo, Peng, Yi, Huang, Yan, Zheng, Ruping, Yu, Haiyang, Wang, Jianlong, Hu, Minghua, Miao, Jinglei, Li, Jinsong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438489/
https://ncbi.nlm.nih.gov/pubmed/32814762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02847-6
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