WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m(6)A-dependent manner

N(6)-methyladenosine (m(6)A) regulators are involved in the progression of various cancers via regulating m(6)A modification. However, the potential role and mechanism of the m(6)A modification in osteosarcoma remains obscure. In this study, WTAP was found to be highly expressed in osteosarcoma tiss...

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Publicat a:Cell Death Dis
Autors principals: Chen, Shijie, Li, Yuezhan, Zhi, Shuang, Ding, Zhiyu, Wang, Weiguo, Peng, Yi, Huang, Yan, Zheng, Ruping, Yu, Haiyang, Wang, Jianlong, Hu, Minghua, Miao, Jinglei, Li, Jinsong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438489/
https://ncbi.nlm.nih.gov/pubmed/32814762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02847-6
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