WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m(6)A-dependent manner

N(6)-methyladenosine (m(6)A) regulators are involved in the progression of various cancers via regulating m(6)A modification. However, the potential role and mechanism of the m(6)A modification in osteosarcoma remains obscure. In this study, WTAP was found to be highly expressed in osteosarcoma tiss...

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Publicado en:Cell Death Dis
Autores principales: Chen, Shijie, Li, Yuezhan, Zhi, Shuang, Ding, Zhiyu, Wang, Weiguo, Peng, Yi, Huang, Yan, Zheng, Ruping, Yu, Haiyang, Wang, Jianlong, Hu, Minghua, Miao, Jinglei, Li, Jinsong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438489/
https://ncbi.nlm.nih.gov/pubmed/32814762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02847-6
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