Tisp40 Induces Tubular Epithelial Cell GSDMD-Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via NF-κB Signaling

Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). As a transcription factor, the Transcript induced in spermiogenesis 40 (Tisp40) has been found to be involved in renal IRI. However, the role of Tisp40 in tubular epithelial cell (TEC) pyroptosis of renal IRI rema...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Xiao, Chengcheng, Zhao, Haijun, Zhu, Hai, Zhang, Yingyu, Su, Qiuju, Zhao, Feng, Wang, Renhe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438479/
https://ncbi.nlm.nih.gov/pubmed/32903383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00906
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