Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium

Morphogens are important signalling molecules for tissue development and their secretion requires tight regulation. In the wing imaginal disc of flies, the morphogen Wnt/Wingless is apically presented by the secreting cell and re-internalized before final long-range secretion. Why Wnt molecules unde...

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Dades bibliogràfiques
Publicat a:Development
Autors principals: Linnemannstöns, Karen, Witte, Leonie, Karuna M, Pradhipa, Kittel, Jeanette Clarissa, Danieli, Adi, Müller, Denise, Nitsch, Lena, Honemann-Capito, Mona, Grawe, Ferdinand, Wodarz, Andreas, Gross, Julia Christina
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438013/
https://ncbi.nlm.nih.gov/pubmed/32611603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.185421
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