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Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium

Morphogens are important signalling molecules for tissue development and their secretion requires tight regulation. In the wing imaginal disc of flies, the morphogen Wnt/Wingless is apically presented by the secreting cell and re-internalized before final long-range secretion. Why Wnt molecules unde...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Linnemannstöns, Karen, Witte, Leonie, Karuna M, Pradhipa, Kittel, Jeanette Clarissa, Danieli, Adi, Müller, Denise, Nitsch, Lena, Honemann-Capito, Mona, Grawe, Ferdinand, Wodarz, Andreas, Gross, Julia Christina
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438013/
https://ncbi.nlm.nih.gov/pubmed/32611603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.185421
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