Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

Humoral responses in coronavirus disease 2019 (COVID-19) are often of limited durability, as seen with other human coronavirus epidemics. To address the underlying etiology, we examined post mortem thoracic lymph nodes and spleens in acute SARS-CoV-2 infection and observed the absence of germinal ce...

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Publicat a:Cell
Autors principals: Kaneko, Naoki, Kuo, Hsiao-Hsuan, Boucau, Julie, Farmer, Jocelyn R., Allard-Chamard, Hugues, Mahajan, Vinay S., Piechocka-Trocha, Alicja, Lefteri, Kristina, Osborn, Matthew, Bals, Julia, Bartsch, Yannic C., Bonheur, Nathalie, Caradonna, Timothy M., Chevalier, Josh, Chowdhury, Fatema, Diefenbach, Thomas J., Einkauf, Kevin, Fallon, Jon, Feldman, Jared, Finn, Kelsey K., Garcia-Broncano, Pilar, Hartana, Ciputra Adijaya, Hauser, Blake M., Jiang, Chenyang, Kaplonek, Paulina, Karpell, Marshall, Koscher, Eric C., Lian, Xiaodong, Liu, Hang, Liu, Jinqing, Ly, Ngoc L., Michell, Ashlin R., Rassadkina, Yelizaveta, Seiger, Kyra, Sessa, Libera, Shin, Sally, Singh, Nishant, Sun, Weiwei, Sun, Xiaoming, Ticheli, Hannah J., Waring, Michael T., Zhu, Alex L., Alter, Galit, Li, Jonathan Z., Lingwood, Daniel, Schmidt, Aaron G., Lichterfeld, Mathias, Walker, Bruce D., Yu, Xu G., Padera, Robert F., Pillai, Shiv
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437499/
https://ncbi.nlm.nih.gov/pubmed/32877699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.08.025
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