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A programmable fate decision landscape underlies single-cell aging in yeast

Chromatin instability and mitochondrial decline are conserved processes that contribute to cellular aging. Although both processes have been explored individually in the context of their distinct signaling pathways, the mechanism that determines which process dominates during aging of individual cel...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Li, Yang, Jiang, Yanfei, Paxman, Julie, O’Laughlin, Richard, Klepin, Stephen, Zhu, Yuelian, Pillus, Lorraine, Tsimring, Lev S., Hasty, Jeff, Hao, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437498/
https://ncbi.nlm.nih.gov/pubmed/32675375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax9552
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