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A programmable fate decision landscape underlies single-cell aging in yeast

Chromatin instability and mitochondrial decline are conserved processes that contribute to cellular aging. Although both processes have been explored individually in the context of their distinct signaling pathways, the mechanism that determines which process dominates during aging of individual cel...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: Li, Yang, Jiang, Yanfei, Paxman, Julie, O’Laughlin, Richard, Klepin, Stephen, Zhu, Yuelian, Pillus, Lorraine, Tsimring, Lev S., Hasty, Jeff, Hao, Nan
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437498/
https://ncbi.nlm.nih.gov/pubmed/32675375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax9552
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