Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics

Although genetic mutations that alter organism’s average lifespans have been identified in aging research, our understanding of the dynamic changes during aging remains limited. Here, we integrate single-cell imaging, microfluidics, and computational modeling to investigate phenotypic divergence and...

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Publicat a:Cell Syst
Autors principals: Jin, Meng, Li, Yang, O’Laughlin, Richard, Bittihn, Philip, Pillus, Lorraine, Tsimring, Lev S., Hasty, Jeff, Hao, Nan
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514117/
https://ncbi.nlm.nih.gov/pubmed/30852250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.02.002
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