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RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an adult-onset, fatal neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. While pathogenic mutations in the DNA/RNA-binding protein Matrin-3 (MATR3) are linked to ALS and distal myopathy, the molecular mecha...
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| 發表在: | Acta Neuropathol Commun |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7437177/ https://ncbi.nlm.nih.gov/pubmed/32811564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01021-5 |
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