SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

INTRODUCTION: Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis (PD). Combination therapies are emerging as a promising treatment for tissue damage. Here, we investigated the therapeutic potential of SIRT1-modified human umbilical cord mesenchymal stem cells (hUCMSCs) fo...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Guo, Yanhong, Wang, Liuwei, Gou, Rong, Wang, Yulin, Shi, Xiujie, Pang, Xinxin, Tang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7436980/
https://ncbi.nlm.nih.gov/pubmed/32811535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01878-2
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