Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells

Breast cancer is considered as one of the most aggressive types of cancer. Acquired therapeutic resistance is the major cause of chemotherapy failure in breast cancer patients. To overcome this resistance and to improve the efficacy of treatment, drug combination is employed as a promising approach...

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Udgivet i:Molecules
Main Authors: Abdallah, Mohamed E., El-Readi, Mahmoud Zaki, Althubiti, Mohammad Ahmad, Almaimani, Riyad Adnan, Ismail, Amar Mohamed, Idris, Shakir, Refaat, Bassem, Almalki, Waleed Hassan, Babakr, Abdullatif Taha, Mukhtar, Mohammed H., Abdalla, Ashraf N., Idris, Omer Fadul
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7436112/
https://ncbi.nlm.nih.gov/pubmed/32722075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153355
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