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LY294002 and rapamycin co-operate to inhibit T-cell proliferation
1. T-cell proliferation is critical for mounting an effective adaptive immune response. It is regulated by signals through the T-cell receptor, through co-stimulation and through cytokines such as interleukin-2 (IL-2). Phosphatidylinositol 3-kinase (PI3K) lies downstream of each of these pathways an...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576062/ https://ncbi.nlm.nih.gov/pubmed/15778701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706061 |
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