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Efficient Palladium-Catalyzed Synthesis of 2-Aryl Propionic Acids
A flexible two-step, one-pot procedure was developed to synthesize 2-aryl propionic acids including the anti-inflammatory drugs naproxen and flurbiprofen. Optimal results were obtained in the presence of the novel ligand neoisopinocampheyldiphenylphosphine (NISPCPP) (9) which enabled the efficient s...
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| Veröffentlicht in: | Molecules |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7435766/ https://ncbi.nlm.nih.gov/pubmed/32731527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153421 |
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