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Chemistry of Fluorinated Pyrimidines in the Era of Personalized Medicine
We review developments in fluorine chemistry contributing to the more precise use of fluorinated pyrimidines (FPs) to treat cancer. 5-Fluorouracil (5-FU) is the most widely used FP and is used to treat > 2 million cancer patients each year. We review methods for 5-FU synthesis, including the inco...
Guardat en:
| Publicat a: | Molecules |
|---|---|
| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7435603/ https://ncbi.nlm.nih.gov/pubmed/32751071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153438 |
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