Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production

Modified Vaccinia Ankara (MVA) virus is a promising vector for vaccination against various challenging pathogens or the treatment of some types of cancers, requiring a high amount of virions per dose for vaccination and gene therapy. Upstream process intensification combining perfusion technologies,...

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Bibliographic Details
Published in:Biotechnol J
Main Authors: Gränicher, Gwendal, Tapia, Felipe, Behrendt, Ilona, Jordan, Ingo, Genzel, Yvonne, Reichl, Udo
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435511/
https://ncbi.nlm.nih.gov/pubmed/32762152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.202000024
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