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Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response

Caveolin-1 (CAV1), is a broadly expressed, membrane-associated scaffolding protein that acts both, as a tumor suppressor and a promoter of metastasis, depending on the type of cancer and stage. CAV1 is downregulated in human tumors, tumor cell lines and oncogene-transformed cells. The tumor suppress...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Díaz, María I., Díaz, Paula, Bennett, Jimena Castillo, Urra, Hery, Ortiz, Rina, Orellana, Pamela Contreras, Hetz, Claudio, Quest, Andrew F. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434918/
https://ncbi.nlm.nih.gov/pubmed/32811828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02792-4
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