Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy

The systemic decline in autophagic activity with age impairs homeostasis in several tissues, leading to age-related diseases. A mechanistic understanding of adipocyte dysfunction with age could help to prevent age-related metabolic disorders, but the role of autophagy in aged adipocytes remains uncl...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yamamuro, Tadashi, Kawabata, Tsuyoshi, Fukuhara, Atsunori, Saita, Shotaro, Nakamura, Shuhei, Takeshita, Hikari, Fujiwara, Mari, Enokidani, Yusuke, Yoshida, Gota, Tabata, Keisuke, Hamasaki, Maho, Kuma, Akiko, Yamamoto, Koichi, Shimomura, Iichiro, Yoshimori, Tamotsu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434891/
https://ncbi.nlm.nih.gov/pubmed/32811819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17985-w
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