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Continuous in-line homogenization process for scale-up production of naltrexone-loaded PLGA microparticles
Injectable, long-acting drug delivery systems provide effective drug concentrations in the blood for up to 6 months. Naltrexone-loaded poly(lactide-co-glycolide) (PLGA) microparticles were prepared using an in-line homogenization method. It allows the transition from a laboratory scale to scale-up p...
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| Pubblicato in: | J Control Release |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7434690/ https://ncbi.nlm.nih.gov/pubmed/32645336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.06.023 |
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