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Continuous in-line homogenization process for scale-up production of naltrexone-loaded PLGA microparticles

Injectable, long-acting drug delivery systems provide effective drug concentrations in the blood for up to 6 months. Naltrexone-loaded poly(lactide-co-glycolide) (PLGA) microparticles were prepared using an in-line homogenization method. It allows the transition from a laboratory scale to scale-up p...

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書目詳細資料
發表在:J Control Release
Main Authors: Sharifi, Farrokh, Otte, Andrew, Yoon, Gwangheum, Park, Kinam
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434690/
https://ncbi.nlm.nih.gov/pubmed/32645336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.06.023
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