Whole‐exome sequencing and genome‐wide association studies identify novel sarcopenia risk genes in Han Chinese

Sarcopenia is a complex polygenic disease, and its molecular mechanism is still unclear. Whole lean body mass (WLBM) is a heritable trait predicting sarcopenia. To identify genomic loci underlying, we performed a whole‐exome sequencing (WES) of WLBM variation with high sequencing depth (more than 40...

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Veröffentlicht in:Mol Genet Genomic Med
Hauptverfasser: Ran, Shu, He, Xiao, Jiang, Zi‐Xuan, Liu, Yu, Zhang, Yu‐Xue, Zhang, Lei, Gu, Gui‐Shan, Pei, Yufang, Liu, Bao‐Lin, Tian, Qing, Zhang, Yong‐Hong, Wang, Jing‐Yu, Deng, Hong‐Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434604/
https://ncbi.nlm.nih.gov/pubmed/32478482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1267
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