Whole‐exome sequencing and genome‐wide association studies identify novel sarcopenia risk genes in Han Chinese

Abstract Sarcopenia is a complex polygenic disease, and its molecular mechanism is still unclear. Whole lean body mass (WLBM) is a heritable trait predicting sarcopenia. To identify genomic loci underlying, we performed a whole‐exome sequencing (WES) of WLBM variation with high sequencing depth (mor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shu Ran, Xiao He, Zi‐Xuan Jiang, Yu Liu, Yu‐Xue Zhang, Lei Zhang, Gui‐Shan Gu, Yufang Pei, Bao‐Lin Liu, Qing Tian, Yong‐Hong Zhang, Jing‐Yu Wang, Hong‐Wen Deng
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-08-01
Colecção:Molecular Genetics & Genomic Medicine
Assuntos:
Sarcopenia
single‐nucleotide polymorphism (SNP)
whole lean body mass (WLBM)
whole‐exome sequencing (WES)
Acesso em linha:https://doi.org/10.1002/mgg3.1267
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados