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Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa

Antibiotics are losing efficacy due to the rapid evolution and spread of resistance. Treatments targeting bacterial virulence factors have been considered as alternatives because they target virulence instead of pathogen viability, and should therefore exert weaker selection for resistance than conv...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Rezzoagli, Chiara, Archetti, Martina, Mignot, Ingrid, Baumgartner, Michael, Kümmerli, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433856/
https://ncbi.nlm.nih.gov/pubmed/32810152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000805
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