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Probing the evolutionary robustness of two repurposed drugs targeting iron uptake in Pseudomonas aeruginosa
LAY SUMMARY: We probed the evolutionary robustness of two antivirulence drugs, gallium and flucytosine, targeting the iron-scavenging pyoverdine in the opportunistic pathogen Pseudomonas aeruginosa. Using an experimental evolution approach in human serum, we showed that antivirulence treatments are...
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| Publicat a: | Evol Med Public Health |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6234326/ https://ncbi.nlm.nih.gov/pubmed/30455950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eoy026 |
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