Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NF-κB Signaling Pathway

Cerebral ischemia is a major cause of brain dysfunction, neuroinflammation and oxidative stress have been implicated in the pathophysiological process of cerebral ischemia/reperfusion injury. Celastrol is a potent inhibitor of inflammation and oxidative stress that has little toxicity. The present s...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Zhang, Bo, Zhong, Qi, Chen, Xuhui, Wu, Xi, Sha, Rong, Song, Guizhi, Zhang, Chuanhan, Chen, Xiangdong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433406/
https://ncbi.nlm.nih.gov/pubmed/32848589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00847
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